Current Research in Therapeutic Targets
Alzheimer's disease (AD) as of now exhibits one of the greatest medicinal services issues in the created nations. There is no successful treatment equipped for backing off infection movement. As of late the fundamental concentrate of research on novel pharmacotherapies depended on the amyloidogenic speculation of AD, which places that the beta amyloid (Aβ) peptide is primarily in charge of subjective hindrance and neuronal demise. The objective of such medicines is (a) to diminish Aβ creation through the restraint of β and γ secretase chemicals and (b) to advance disintegration of existing cerebral Aβ plaques. Be that as it may, this approach has turned out to be just unobtrusively viable. Late investigations propose an option methodology fixated on the restraint of the downstream Aβ flagging, especially at the neural connection. Aβ oligomers may cause deviant N-methyl-D-aspartate receptor (NMDAR) initiation postsynaptically by shaping buildings with the phone surface prion protein (PrPC). PrPC is enhanced at the neuronal postsynaptic thickness, where it collaborates with Fyn tyrosine kinase. Fyn enactment happens when Aβ is bound to PrPC-Fyn complex. Fyn causes tyrosine phosphorylation of the NR2B subunit of metabotropic glutamate receptor 5 (mGluR5). Fyn kinase blockers masitinib and saracatinib have ended up being effective in treating AD side effects in trial mouse models of the illness.
- Amyloid Plaques
- Loss of Neuronal Connections and Cell Death
- Vascular Contributions to Alzheimer’s Disease
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- Pathophysiology of Dementia - Euro Dementia 2025 (Germany)
- Patient Care and Rehabilitation - BRAIN DISORDER - 2025 (France)
- Pediatric and Adolescent Mental Health - EURO MENTAL DISORDER 2025 (France)
- Pediatric and Adult Epilepsy Transition - Epilepsy 2025 (France)
- Pediatric Epilepsy - Epilepsy 2025 (France)
- Pediatric Neurology - Neuroscience Congress 2025 (Canada)
- Pediatric Neurology - Neurogenetics 2025 (Canada)
- Pediatric Neurology - Stroke Summit 2025 (Canada)
- Pediatric Neurology - NEUROSCIENCE_2025 (France)
- Pediatric Neurology - CNS 2025 (Germany)
- Pediatric Neurology and Epilepsy - Cognitive Neuroscience 2025 (Switzerland)
- Pediatric Neurology: Developmental and Genetic Insights - Neurology Congress 2025 (France)
- Pediatric Neurology: Disorders and Innovations - Neurological Disorders 2025 (Netherlands)
- Pediatric Neurosurgery - Neuro Surgery 2025 (UK)
- Pediatric Sleep Solutions - SLEEP DISORDER 2025 (Netherlands)
- Pediatric Spine Disorders and Early Intervention Strategies - Spine 2025 (Italy)
- Personalized Medicine and Biomarker-Driven Approaches in Neurodegenerative Diseases - Vascular Dementia Congress 2025 (Switzerland)
- Personalized Sleep Therapies - SLEEP DISORDER 2025 (Netherlands)
- Pharmacological Advances in Dementia Treatment - Euro Dementia 2025 (Germany)
- Pioneering Techniques in Awake Craniotomy - Neuro Surgery 2025 (UK)
- Post-Viral Neuromuscular Syndromes and Long COVID - Neurology Conference 2026 (France)
- Precision Medicine and Genomics in Spinal Disorders - Spine 2025 (Italy)
- Protein Misfolding and Aggregation in Neurodegenerative Disorders - Vascular Dementia Congress 2025 (Switzerland)
- Psychiatric Comorbidities in Neurological Disorders - Neurology Congress 2025 (France)
- Psychiatric Disorders - Neuroscience 2025 (France)
- Psychiatric neuroscience - Neuroscience Congress-2025 (France)
- Psychiatry - Mental Health Congress 2025 (France)
- Psychiatry and Psychology - Neurogenetics 2025 (Canada)
- Psychiatry Mental Health Disorders - Dementia-2025 (Switzerland)
- Psychological Research - Mental Health Congress 2025 (France)
- Psychotherapy and Counselling - Mental Health Congress 2025 (France)
- Public Health Initiatives and Advocacy - Alzheimers-2025 (France)
- Rapid Sleep Diagnostics - SLEEP DISORDER 2025 (Netherlands)
- Rare Neurological Disorders and Case Studies - Neurological Disorders 2025 (Netherlands)
- Recent Studies & Case Reports - Dementia-2025 (Switzerland)
- Regenerative Medicine and Stem Cell Therapy for Spinal Disorders - Spine 2025 (Italy)
- Rehabilitation and Neuroplasticity - NEUROSCIENCE_2025 (France)
- Rehabilitation and Restorative Therapy in Stroke - Stroke Summit 2025 (Canada)
- Risk factor and Prevention of Stroke - Stroke Summit 2025 (Canada)
- Risk factors, Diagnosis, Medications, and Recovery - Stroke Meeting 2025 (France)
- Robotic Neurosurgery - Neuroscience Congress 2025 (Canada)
- Robotic Neurosurgery - CNS 2025 (Germany)
- Role of Inflammation and Oxidative Stress in Vascular Dementia - Vascular Dementia Congress 2025 (Switzerland)
- Schizophrenia - Neuroscience Congress-2025 (France)
- Screen Time Effects - SLEEP DISORDER 2025 (Netherlands)
- Sex, Gender, and Hormonal Influences in Neuro-Muscle Disorders - Neurology Conference 2026 (France)
- Shift Worker Sleep Tips - SLEEP DISORDER 2025 (Netherlands)
- Skull Base Surgery: Techniques and Outcomes - Neuro Surgery 2025 (UK)
- Sleep Apnea Device Overview - SLEEP DISORDER 2025 (Netherlands)
- Sleep disorder - Mental Health Congress 2025 (France)
- Sleep Disorders - BRAIN DISORDER - 2025 (France)
- Sleep Disorders and Circadian Neuroscience - NEUROSCIENCE_2025 (France)
- Sleep Disorders and Their Neurological Implications - Neurology Congress 2025 (France)
- Sleep Disorders: Pathophysiology and Management - Neurological Disorders 2025 (Netherlands)
- Sleep Hygiene Essentials - SLEEP DISORDER 2025 (Netherlands)
- Sleep in Mental Health - SLEEP DISORDER 2025 (Netherlands)
- Sleep Myths vs. Facts - SLEEP DISORDER 2025 (Netherlands)
- Spinal Biomechanics and Kinesiology - Spine 2025 (Italy)
- Spinal Cord Injuries: Innovations and Rehabilitation - Neurological Disorders 2025 (Netherlands)
- Spinal Cord Injuries: Surgical Management and Rehabilitation - Neuro Surgery 2025 (UK)
- Spinal Cord Injury: Advances in Treatment and Regeneration - Neurology Congress 2025 (France)
- Spinal Cord Stimulation and Neuromuscular Recovery - Neurology Conference 2026 (France)
- Spinal Deformities: Diagnosis and Treatment Innovations - Spine 2025 (Italy)
- Spinal Disorders and Spine Surgery - CNS 2025 (Germany)
- Spinal Tumors: Diagnosis, Treatment, and Outcomes - Spine 2025 (Italy)
- Spine and Spinal disorders - Neuroscience Congress 2025 (Canada)
- Spine Disorders in the Aging Population: Challenges and Solutions - Spine 2025 (Italy)
- Sports-Related Spinal Injuries: Diagnosis, Prevention, and Treatment - Spine 2025 (Italy)
- Sports-Related Spine Injuries and Rehabilitation - Spine 2025 (Italy)
- Stem Cell Therapy and Regenerative Medicine in Neurosurgery - Neuro Surgery 2025 (UK)
- Stem Cells & Brain Repair - Neuroscience 2025 (France)
- Stigma and Mental Health - EURO MENTAL DISORDER 2025 (France)
- Stress and Sleep Connection - SLEEP DISORDER 2025 (Netherlands)
- Stroke - Stroke Summit 2025 (Canada)
- Stroke & Neurological Disorders - Neuroscience 2025 (France)
- Stroke and Cerebrovascular Diseases - Stroke Meeting 2025 (France)
- Stroke and Cerebrovascular Disorders - BRAIN DISORDER - 2025 (France)
- Stroke and Cerebrovascular Disorders - NEUROSCIENCE_2025 (France)
- Stroke and Neurological Disorders - Neuroscience Congress 2025 (Canada)
- Stroke and Post-Stroke Dementia: Prevention and Management - Vascular Dementia Congress 2025 (Switzerland)
- Stroke and recovery - Neuroscience Congress-2025 (France)
- Stroke Management and Cerebrovascular Disorders - Neurological Disorders 2025 (Netherlands)
- Stroke Rehabilitation and Brain Hemorrhage - Stroke Meeting 2025 (France)
- Stroke risk, phenotypes, and death in COVID-19 - Stroke Meeting 2025 (France)
- Substance Abuse and Mental Health - EURO MENTAL DISORDER 2025 (France)
- Suicide Prevention Strategies - EURO MENTAL DISORDER 2025 (France)
- Surgical Frontiers in Peripheral Nerve Injuries - Neurology Conference 2026 (France)
- Targeting Neurovascular Dysfunction in Neurodegenerative Diseases - Vascular Dementia Congress 2025 (Switzerland)
- Tauopathies and Synucleinopathies: Molecular Mechanisms of Neurodegeneration - Vascular Dementia Congress 2025 (Switzerland)
- Technological Innovations in Mental Health - EURO MENTAL DISORDER 2025 (France)
- The Future of Neurodegenerative Disease Therapy: Stem Cells and Regenerative Medicine - Vascular Dementia Congress 2025 (Switzerland)
- The Future of Spinal Robotics and Smart Wearable Technologies - Spine 2025 (Italy)
- The Impact of Epilepsy on Cognitive Function and Quality of Life - Epilepsy 2025 (France)
- The Impact of Epilepsy on Cognitive Function and Quality of Life - Epilepsy 2025 (France)
- The Impact of Space Travel and Microgravity on the Spine - Spine 2025 (Italy)
- The Intersection of Mental Health and Chronic Spine Disorders - Spine 2025 (Italy)
- The Role of Neurostimulation in Epilepsy Management - Epilepsy 2025 (France)
- The Role of Neurostimulation in Epilepsy Management - Epilepsy 2025 (France)
- The Role of Nutrition and Lifestyle in Spinal Health - Spine 2025 (Italy)
- The Role of Seizure Monitoring and Technology in Epilepsy Management - Epilepsy 2025 (France)
- Transcranial Magnetic Stimulation and Neuromuscular Plasticity - Neurology Conference 2026 (France)
- Traumatic brain injury - Neuroscience Congress-2025 (France)
- Traumatic Brain Injury - Brain Disorders-2025 (USA)
- Traumatic Brain Injury (TBI) and Neurotrauma - Neuro Surgery 2025 (UK)
- Vascular Dementia - Euro Dementia 2025 (Germany)
- Virtual Reality and Mixed Reality in Neurorehabilitation - Neurology Conference 2026 (France)
- Women's Mental Health - EURO MENTAL DISORDER 2025 (France)
- Women’s Sleep Health - SLEEP DISORDER 2025 (Netherlands)
- Workplace Mental Health - EURO MENTAL DISORDER 2025 (France)