Current Research in Therapeutic Targets
Alzheimer's disease (AD) as of now exhibits one of the greatest medicinal services issues in the created nations. There is no successful treatment equipped for backing off infection movement. As of late the fundamental concentrate of research on novel pharmacotherapies depended on the amyloidogenic speculation of AD, which places that the beta amyloid (Aβ) peptide is primarily in charge of subjective hindrance and neuronal demise. The objective of such medicines is (a) to diminish Aβ creation through the restraint of β and γ secretase chemicals and (b) to advance disintegration of existing cerebral Aβ plaques. Be that as it may, this approach has turned out to be just unobtrusively viable. Late investigations propose an option methodology fixated on the restraint of the downstream Aβ flagging, especially at the neural connection. Aβ oligomers may cause deviant N-methyl-D-aspartate receptor (NMDAR) initiation postsynaptically by shaping buildings with the phone surface prion protein (PrPC). PrPC is enhanced at the neuronal postsynaptic thickness, where it collaborates with Fyn tyrosine kinase. Fyn enactment happens when Aβ is bound to PrPC-Fyn complex. Fyn causes tyrosine phosphorylation of the NR2B subunit of metabotropic glutamate receptor 5 (mGluR5). Fyn kinase blockers masitinib and saracatinib have ended up being effective in treating AD side effects in trial mouse models of the illness.
- Amyloid Plaques
- Loss of Neuronal Connections and Cell Death
- Vascular Contributions to Alzheimer’s Disease
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Current Research in Therapeutic Targets Conference Speakers
Recommended Sessions
- Alzheimers disease and Dementia
- Alzheimers Disease and Type 2 Diabetes
- Animal Models and Translational Medicine
- Behavioral Problems in Alzheimers disease
- Care Practice and Awareness
- Current Research in Therapeutic Targets
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- Postpartum Depression - DEPRESSION CONGRESS 2024 (France)
- Precision Medicine and Genetics - Neurology Conference 2024 (Scotland)
- Precision Medicine in Epilepsy: Targeting Specific Pathways for Optimal Results - Epilepsy 2024 (France)
- Precision Medicine in Neurology: Personalized Approaches for Optimal Patient Care - Stroke Global-2024 (Italy)
- Psychiatric Rehabilitation - Mental Health Congress 2024 (France)
- Psychiatric Syndromes - DEPRESSION CONGRESS 2024 (France)
- Psychiatry - Neuro Surgery 2024 (France)
- Psychiatry and Psychology - Neurology Congress 2024 (France)
- Psychiatry and Psychology - Dementia 2024 (UK)
- Psychiatry and Psychology - Neurology Conference 2024 (Scotland)
- Psychiatry and Psychology - Dementia Care 2024 (UK)
- Psychiatry and Psychology - NEURO SCIENCE 2024 (UK)
- Psychoanalysis - Mental Health Congress 2024 (France)
- Psychoeducation - Mental Health Congress 2024 (France)
- Psychology - Alzheimers-2024 (Netherlands)
- Psychology & Psychotherapy - Mental Health Congress 2024 (France)
- Psychology and Neuroscience - BRAIN DISORDER- 2024 (France)
- Psychology and Psychiatric Nursing in Mental Health Care - EURO MENTAL DISORDER 2024 (France)
- Psychoneuroimmunology - Mental Health Congress 2024 (France)
- Psychopathology - Mental Health Congress 2024 (France)
- Psychopharmacology - Mental Health Congress 2024 (France)
- Psychopharmacology - NEURO SCIENCE 2024 (UK)
- Psychophysiology - Mental Health Congress 2024 (France)
- Psychosocial Aspects of Child Neurology - Child Neurology 2024 (UK)
- Psychosomatic Disorders - Neurology Conference 2024 (Scotland)
- Psychosomatic Medicine - Mental Health Congress 2024 (France)
- Psychosomatic medicine - NEURO SCIENCE 2024 (UK)
- Psychosomatic Medicine and Sleep Medicine - Euro Neuro 2024 (UK)
- Psychotherapy/Analysis - Euro Neuro 2024 (UK)
- Psychotic Depressions - DEPRESSION CONGRESS 2024 (France)
- Public Awareness - Alzheimers-2024 (Netherlands)
- RADIOLOGY - NEURO CONGRESS 2024 (Italy)
- Radiomics and Artificial Intelligence (AI) - Spine Congress 2024 (Netherlands)
- Recent Developments in Dementia Treatment - Alzheimers-2024 (Netherlands)
- Rehabilitation and Restorative Therapy in Stroke - Stroke Summit 2024 (Germany)
- Resistant Depressions - DEPRESSION CONGRESS 2024 (France)
- Risk Assessment and Prevention of Stroke. - Neurological Disorders 2024 (UK)
- Risk factor and Prevention of Stroke - Stroke Summit 2024 (Germany)
- Robotic Neurosurgery - Neuroscience Congress 2024 (Canada)
- Robotic Neurosurgery - NEURO SCIENCE 2024 (UK)
- Robotic Technology in Spine Surgery - Spine Congress 2024 (Netherlands)
- Schizophrenia/Psychosis - Euro Neuro 2024 (UK)
- Seasonal Affective Disorder (SAD) - DEPRESSION CONGRESS 2024 (France)
- Seizure Disorder and Epilepsy. - Neurological Disorders 2024 (UK)
- Seizure Disorders - Euro Neuro 2024 (UK)
- Seizure Forecasting: The Future of Early Intervention in Epilepsy - Epilepsy 2024 (France)
- Situational or Reactive Depression - DEPRESSION CONGRESS 2024 (France)
- Sleep disorders - Dementia 2024 (UK)
- Sleep disorders - Dementia Care 2024 (UK)
- Social Psychiatry and Psychiatric Epidemiology - Mental Health Congress 2024 (France)
- Space Neuroscience - Neurological Disorders 2024 (Australia)
- Spasticity, Spinal Pain, and Spinal Infection - Spine Congress 2024 (Netherlands)
- Spinal Arthroplasty and Motion Preservation - Spine Congress 2024 (Netherlands)
- Spinal biologics - Spine Congress 2024 (Netherlands)
- Spinal cord injury - Spine 2024 (Italy)
- Spinal Cord Injury - Spine Congress 2024 (Netherlands)
- Spinal deformity - Spine 2024 (Italy)
- Spinal Fusion - Spine 2024 (Italy)
- Spinal Imaging - Spine Congress 2024 (Netherlands)
- Spinal Implants market analysis & Entrepreneurs Investment Meet - Spine 2024 (Italy)
- Spinal Injections - Spine 2024 (Italy)
- Spinal Interventional Radiology - Spine Congress 2024 (Netherlands)
- Spinal Manipulation - Spine 2024 (Italy)
- Spinal Pathology - Spine Congress 2024 (Netherlands)
- Spinal Rehabilitation and Nursing Care - Spine Congress 2024 (Netherlands)
- Spine and Spinal Disorder. - Neurological Disorders 2024 (UK)
- Spine and Spinal disorders - Neuroscience Congress 2024 (Canada)
- Spine and Spinal Disorders - Neurology Conference 2024 (Scotland)
- Spine and Spinal disorders - NEURO SCIENCE 2024 (UK)
- Spine and spinal Disorders - Spine 2024 (Italy)
- Spine and spinal Disorders - Spine 2024 (Italy)
- Spine and Spinal Disorders - Neurology Congress 2024 (France)
- Spine and spinal stenosis - Spine 2024 (Italy)
- Spine Diseases - Spine 2024 (Italy)
- Spine Fracture - Spine 2024 (Italy)
- Spine Infection - Spine 2024 (Italy)
- Spine Surgery - Spine Congress 2024 (Netherlands)
- Spine surgery & therapy - Spine 2024 (Italy)
- Stages, types and Treatment of Alzheimer’s disease and Dementia - Dementia 2024 (UK)
- Stages, types and Treatment of Alzheimer’s disease and Dementia - Dementia Care 2024 (UK)
- Stem Cell Therapies - BRAIN DISORDER- 2024 (France)
- Stem Cell Therapy - Spine 2024 (Italy)
- Stem Cells and Neuroregeneration - Neurological Disorders 2024 (Australia)
- Stigma Reduction and Mental Health Advocacy - EURO MENTAL DISORDER 2024 (France)
- Stress Management - DEPRESSION CONGRESS 2024 (France)
- Stress, Anxiety and Depression - Mental Health Congress 2024 (France)
- Stroke - Stroke Summit 2024 (Germany)
- Stroke - Neurological Disorders 2024 (UK)
- Stroke and its Management. - Neurological Disorders 2024 (UK)
- Stroke and Mental Health. - Neurological Disorders 2024 (UK)
- Stroke and Vascular Neurology - Neuroscience 2024 (Netherlands)
- Stroke Epidemiology and Public Health Interventions - Stroke Meeting 2024 (France)
- Stroke in Young Adults: Challenges and Insights - Stroke Meeting 2024 (France)
- Stroke Prevention and Rehabilitation: Integrating Evidence-based Strategies - Stroke Global-2024 (Italy)
- Stroke Prevention in High-Risk Populations - Stroke Meeting 2024 (France)
- Stroke Rehabbition and Recovery - Neurological Disorders 2024 (UK)
- Stroke Rehabilitation: Novel Therapeutic Approaches - Stroke Meeting 2024 (France)
- Strokes and Cerebral Hemorrhage - Neurological Disorders 2024 (UK)
- Strokes and Neurocardiology - Alzheimers-2024 (Netherlands)
- Subs Syndromal Depression - DEPRESSION CONGRESS 2024 (France)
- Substance Use Disorders and Dual Diagnosis - EURO MENTAL DISORDER 2024 (France)
- Suicide Prevention - DEPRESSION CONGRESS 2024 (France)
- Suicide Prevention and Crisis Intervention - EURO MENTAL DISORDER 2024 (France)
- Surgical Approaches to the Spine - Spine Congress 2024 (Netherlands)
- Technological Advances in Stroke Prevention - Stroke Meeting 2024 (France)
- Telemedicine in Epilepsy: Bridging Gaps in Remote Patient Management - Epilepsy 2024 (France)
- Telemedicine in Neurology: Expanding Access and Improving Patient Care - Stroke Global-2024 (Italy)
- Therapeutics Approaches for Neurological Disorder - Neurological Disorders 2024 (UK)
- Translational Neuroscience: Bridging the Gap between Research and Clinical Practice - Stroke Global-2024 (Italy)
- Translational Research in Stroke Medicine - Stroke Meeting 2024 (France)
- Trauma and Post-Traumatic Stress Disorder (PTSD) - EURO MENTAL DISORDER 2024 (France)
- Vagus Nerve Stimulation (VNS) - BRAIN DISORDER- 2024 (France)
- Vestibular Disorders - Euro Neuro 2024 (UK)
- Woman’s Mental Health - NEURO SCIENCE 2024 (UK)
- Womens Health in Epilepsy: Hormonal Influences and Reproductive Considerations - Epilepsy 2024 (France)